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"Appearance Off-white powder Assay 98% min Water insoluble 0.5% max Acid degree 0.3% max Acetone insolubles 0.3% max "

Appearance Yellow crystalline powder Identification 1. HPLC: the retention time of the major peak corresponds to that of the standard sample 2. IR: the infrared absorption time spectrum exhibits maximum only at the same as that of the standard sample 3. It gives reaction of chlorides Water content ≤1.0% UV purity ratio ≥4.5 Trichloroammine platinate ≤1.0% Transplatin ≤2.0% Platinum content 64.42%-65.22% Assay( HPLC) 98.0%-102.0% Packing and Storage Preserve in tight containers, protected from light.

Appearance White to off white powder Assay, HPLC 98.0%min Identification IR, HPLC Specific rotation (20/D) -7.0°~ -13° Impurities Total: 1.0% max Individual impurity: 0.5% max Loss on drying 0.5% max metals 0.002% max Bacterial Endotoxins 0.36% max Enantiomeric 2.0%max

Appearance White crystalline powder Identification Positive Color of solution Clear, GY4 max Assay 99-100.5% PH 8.0-9.5 Related substances One: 0.5% max Others: 0.25% max Sulphate 0.02% max metals 0.002% max Selenium 0.003% max Solubility Easily soluble in water,slightly soluble in ethyl alcohol Water 6.0-8.0%

Appearance white or almost white crystalline Assay, （AgNO3 Titration method） ≥98.0% Identification A:Developing colour reaction: Crroesponds B:Developing colour reaction: Crroesponds C: Developing colour reaction: Crroesponds Acidity(PH) 6.0-7.0 Water 6.0%max Residue on igition Max 0.5% Microbial potency(anhydrous) 780u/mg

Appearance A white or light yellow powder, odorless, hygroscpic Identification A,B,C The positive reaction Soluility Very soluble in water, insoluble in acetone,chloroform,ether PH 5.5-7.5 Loss on drying 8.0% max Assay 600 I.U/mg min(dry)

Appearance White crystalline powder Assay 99.0-100.5%min Melting point 128-132℃ Specific optical rotation -15.7?~-17.3? Residue on ignition 0.1% max Loss on drying 0.5%max metals 20ppm max Absence of reducing substance Accords with the specification Clarity and color of the solution Accords with the specification

Appearance white crystalline powder Optical Rotation -96?~~ -106? metals Not more than 10ppm Arsenic Not more than 2ppm Loss on drying Not more than 5% Residue on Ignition Not more than 0.5% Assay Not less than 98.0%

Appearance A white crystalline powder Assay 98.0% to 101.0% Melting point About 185℃ Identification IR Similar with the Reference Spectrum Optical Rotation -15.5°～-17.5° Clearity and color of solution Clear and colourless Metals Not more than 10ppm Arsenic Not more than 2ppm Related Substances Total Not more than 2.0% GSSG Not more than 1.5% Loss on Drying Not more than 0.5% Residue on Ignition Not more than 0.1%

Appearance White or almost white crystalline powder Assay, dry base 99.0-101.0% Identification Melting point: 169.0-172.0 IR: per the spectrum of CRS TLC: As per BP2002 Chemical test: give reaction of primary Aromatic amines Appearance of solution The solution is clear and not more intensely colored than ref. solution Y5,BY5 or GY5 Acidity 0.3ml of 0.1M NaOH Related substances by TLC 0.5% max metals 20ppm max Loss on drying 0.5% max Sulfated ash 0.1% max

BP/EP/USP，99%

Description A white or almost white crystalline powder Identification Conform with spectrum off the reference standard Enantiomer ≤0.50% Related substance 5-Flucytosine ≤0.20% Total impurities ≤1.0% Residual solvents Ethanol ≤0.50% Dichloromethane ≤0.06% DMF ≤0.088% Ethyl acetate ≤0.50% Toluene ≤0.089% Residue on ignition ≤0.20% Specific optical rotation -133゜～-143゜ Water ≤0.50% Metal ≤20ppm Loss on drying ≤1.0% Assay 98.0%-102.0%